Slavery was strictly forbidden in the Northwest Territory. And who devised the plan to organize the Northwest Territory?
Jefferson.
Many of the settlers in Ohio, Indiana and Illinois were from slaveholding states so if they had been allowed to bring slaves with them those states might well have become slave states. That would have changed American history for the worse. I think in Illinois there was a proposal to allow slavery after it became a state which was defeated by a 4-3 margin despite slavery never having been legal there.