IMHO the biggest factor making Dr. Kruse a massive target is, to my knowledge, something he never stated, but is a logical outgrowth of one of his central tenets. As my above Kruse link shows, that tenet is that human evolution has been formed by a long succession of kill-off epidemics caused by intestine-borne viral epidemics.
We see these epidemics today trying to kill off human populations through viruses like Ebola, HIV and monkey pox. There’s no getting around it, these viruses are spread through male-on-male sex. And that makes Dr Kruse a huge target to the left.
The Old Testament of the Holy Bible is pretty clear about what should not be done. Yet, we do it anyway. Then we wonder why everything starts falling apart.