“Muscle fibers are largely composed of myofibrils, but whether radial growth is mediated by an increase in the size of the myofibrils (i.e. myofibril hypertrophy) and/or the number of myofibrils (i.e. myofibrillogenesis) is not known.”
“After extensively validating the automated measurements, we used both mouse and human models of increased mechanical loading to discover that the radial growth of muscle fibers is largely mediated by myofibrillogenesis.”
https://elifesciences.org/articles/92674
Myofibrils are components of the cell. Increasing the number of myofibrils does not change the number of cells.
“the radial growth of muscle fibers is largely mediated by myofibrillogenesis.”
Is equivalent to:
the radial growth of muscle CELLS is largely mediated by myofibrillogenesis.