It may be what God allows when the horsemen at let loose and viruses and plagues sweep the world taking a 1/3 of it out in the last days
But then again, God may allow something completely different to accomplish it.
A big X-class solar flare would do the job. If one as powerful as the Carrington Event of 1859 happened today it would result in the deaths of billions of people.
So, what is the likelihood of this happening?
"The 2021 Astrophysical Journal study analyzing Kepler data suggested that superflares about 10 times more energetic than the Carrington Event may happen about every 3,000 years, and ones about 100 times more energetic may occur about every 6,000 years."