[ConservativeMind]

More than 10% of people over 65 have this issue, and they may naturally know they are at high risk, simply due to having chronic inflammatory diseases.

Fortunately, this can be tested and it appears rapamycin can help correct this runaway mutation. Rapamycin (Sirolimus) is currently available for prescribing. It is most often used for organ transplant recipients.

GoodRX shows it for around $32 a prescription at places like Target and CVS.

In recent years, it has been found to help get rid of dysfunctional cells.

[ConservativeMind]

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[icclearly]

.....it appears rapamycin can help correct this runaway mutation.

So, let me understand your comment. You are suggesting that we rush out and first find a doc to prescribe rapamycin and spend $32 for the miracle drug.

Where is the double-blind placebo-controlled human study that supports your directive?

Why not talk about the effects of exercise and fasting that may have the same or even better effect? And, you don't need a script or a pill for $32. That is if your goal is to improve health and longevity.

Snake oil.

[Pelham]

Rapamycin sounds somewhat similar to Rituximab but vastly less expensive. There might be some overlap in treating autoimmune disorders.

[Tilted Irish Kilt]

(From the article) : " As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations.
Some of the mutations allow these stem cells to self-renew and expand more effectively than their non-mutated counterparts."

This might also explain why many elites on the West Coast have encouraged many older adults and politicians to obtain blood transfusions from younger, and known, donors.
While it may seem ghoulish to many, such transfusions would offset the aging process and replace and help get rid of old dysfunctional cells and the immune cells—accumulate mutations.