As regards STD's and other conditions, as well as as well as suicides in the US among MSM and lesbians and "transgendered" persons:
Overall, the practice pf sodomy has (historically) resulted in a greatly increased incidence of other infectious diseases and effects besides HIV, from Meningitis to premature death. Which diseases includes Chlamydia, Gonorrhea, Hepatitis A and B, HPV, Syphilis, HIV to Meningitis and body dysmorphia and eating disorders and recently Monkey pox. Gay, bisexual, and other men who have sex with men have accounted for 83% of primary and secondary syphilis cases where sex of sex partner was known in the United States. Gay, bisexual, and other men who have sex with men have been found to be 17 times more likely to get anal cancer than heterosexual men. (https://www.cdc.gov/mmwr/volumes/71/wr/mm7138a1.htm)
Vanderbilt University Medical Center states: Men who have sex with men and gay men are at increased risk for certain types of chronic diseases, cancers, and mental health problems… #1: HIV/AIDS. #2: Anal Papilloma #3: Hepatitis #4: Substance Use #5: Depression and Anxiety #6: Sexually Transmitted Diseases (STDs) #7: Prostate, Testicular, and Colon Cancer #8: Alcohol #9: Tobacco #10: Body image problems and obesity. (https://www.vumc.org/lgbtq/key-health-concerns-msm-men-who-have-sex-men)
Anal cancer is particularly one of the diseases that is far more prevalent among MSM than other population groups, being diagnosed in about 2 people out of every 100,000 people in the general population. In contrast, it is estimated that MSMs that are not infected with HIV are 20 times more likely to be diagnosed with anal cancer. HPV is present in approximately 65% of HIV negative MSMs and 95% of MSMs who are HIV positive. Anal cancer is caused by the same strains of HPV (Human Papillomavirus) that cause cervical cancer in women. (https://cancer-network.org/cancer-information/gay-men-and-cancer/anal-cancer-hiv-and-gaybisexual-men)
Related to this is that,
The risk of becoming infected with HIV during condomless anal sex is 10 to 20 times greater than condomless vaginal sex. Because the rectal lining is only one-cell thick, the virus can more easily reach immune cells to infect. (https://www.mtnstopshiv.org/news/rectal-microbicides-fact-sheet)
Also, multiple studies [2017] have found a rise in unprotected sex among men who have sex with men. (https://europepmc.org/article/med/32332483)
Also reported, "People living with HIV in Canada had eight times the risk of Alzheimer’s disease and other non-AIDS-related dementia as their HIV-negative counterparts, and they were diagnosed 12.5 years earlier [which in part may be due to more medical attention], according to an analysis published in BMJ Open.
They also had higher rates of several other age-related chronic conditions....Antiretroviral treatment has been associated with kidney damage and cardiovascular disease, and viral hepatitis and alcohol use—both common among HIV-positive people—can cause liver disease." (https://www.poz.com/article/people-hiv-diagnosed-dementia-13-years-earlier)
Even when their disease is well controlled, people with HIV can develop aging-related conditions such as cardiovascular disease, certain cancers, kidney and liver disease, osteoporosis, and cognitive impairment decades ahead of their HIV-negative counterparts, and their life expectancy is significantly reduced.)
And a new study shows evidence that "HIV-positive people are at an increased risk of age-related diseases such as some cancers, frailty, osteoporosis, kidney disease, and neurocognitive disease. Researchers think that it is the HIV itself that accelerates the aging process by 14 years, rather than medications used to treat it." (https://www.hivplusmag.com/treatment/2015/03/25/study-people-hiv-age-14-years-faster)
Moreover, while (2020) one "life expectancy study has shown that HIV-positive people who start antiretroviral therapy (ART) promptly and have good access to medical care live as long as their HIV-negative peers," yet "the researchers found that HIV-positive people were living with additional health problems for many of those years – on average, they had major co-morbidities 16 years earlier than HIV-negative people." (https://web.archive.org/web/20220625103005/https://www.aidsmap.com/news/mar-2020/yes-same-life-expectancy-hiv-negative-people-far-fewer-years-good-health)
A 2021 study of comparison of dementia incidence and prevalence between individuals (90% male) after age 50 with and without HIV infection in primary care from 2000 to 2016 found that HIV was associated with an 80% increase in dementia diagnosis overall compared with HIV-negative people. (https://www.poz.com/article/even-modern-era-people-hiv-increased-risk-dementia; https://journals.lww.com/aidsonline/Abstract/2022/03010/Comparison_of_dementia_incidence_and_prevalence.13.aspx
In a Danish study of "6,657,456 Danish-born individuals who were at least 15 years old and lived in Denmark from January 1980 through December 2021," in which "3,759 (52.5% assigned male at birth) were identified as transgender at a median age of 22," "there were 92 suicide attempts, 12 suicides, and 245 suicide-unrelated deaths among this group." "Among over 6.6 million individuals, standardized suicide attempt rates per 100,000 person-years were 498 for those who were transgender compared with 71 per 100,000 person-years for those who were not transgender."
"Transgender individuals also had higher rates of mortality not related to suicide (aIRR 1.9, 95% CI 1.6-2.2) and higher rates of all-cause mortality (aIRR 2.0, 95% CI 1.7-2.4) compared with non-transgender individuals." (https://www.medpagetoday.com/)
"Transgender women [worldwide] are 49 times more likely to have HIV than other adults of reproductive age." (https://www.who.int/hiv/topics/transgender/en/)
Transgender women have a higher risk of venous thromboembolism, stroke and meningioma compared to cisgender men and cisgender women. Compared to cisgender men, transgender women have a higher risk of breast cancer and transgender women > 50 years old have a higher risk of fractures.
(https://pubmed.ncbi.nlm.nih.gov/32757514/)
Negative health results from treatment and surgery in transgendering itself are reported from research:
