I think Gino Marchetti was the last one to play with a broken leg. 1956.
In about 2005 I watched a UK game against an instate rival (maybe Louisville?) where one of the QBs sustained a severe leg injury but insisted on playing. I think it was raining too and it went into overtime several times. His teammates literally carried him to the line of scrimmage for the remaining plays. Can’t remember who won but it was pretty inspiring to see. That’s when I realized most college athletes play with heart while most pros play for $$$.