These are incredible doses that are far beyond what doctors would have likely experimented with, before, in my humble opinion.
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https://optimaearth.com/linus-paulings-vitamin-c-therapy-a-personal-experience/
I watched a documentary on Linus Pauling and Vitamin C over 30 years ago. The only thing I remember is Pauling recommended people take mega doses of Vitamin C daily. In fact, he thought it should be available in shakers everywhere like table salt.