Theoretical maximum daily intake of trigonelline via coffee and coffee by-products, (g/day)
Coffee beverages 13.8
Well, it is possible to overdose on caffeine and have a stroke, heart attack etc. It’s apparently happened to people consuming caffeine pills or powder. If you guzzled 14 cups of joe within the space of a couple hours, would you be close to that toxic level of caffeine? Maybe, but I suspect anyone guzzling that much coffee would suffer an upset stomach before they got into such dangerous territory.
1 For coffee by-products, a preparation of tea infusions with 2 g of coffee by-product per 200 mL of cold water was assumed. For further explanation, see text. For coffee beverages, the assumption of weighing-in 2 g of, in this case, ground, roasted coffee beans, was not made as data for the final beverage are available (see Table 2). To account for the outlined worst-case scenario, for each matrix the highest trigonelline content as reported in Table
2 was used in the calculations.