Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Study suggests single dose of psilocybin safe and effective as treatment for major depressive disorder
Medical Xpress / JAMA ^ | Sept. 4, 2023 | Justin Jackson / Charles L. Raison et al / Rachel Yehuda et al

Posted on 09/05/2023 3:02:08 PM PDT by ConservativeMind

click here to read article


Navigation: use the links below to view more comments.
first 1-2021-29 next last
One pill, with non-drug follow up, can remediate depression.
1 posted on 09/05/2023 3:02:08 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 09/05/2023 3:02:40 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

3 posted on 09/05/2023 3:04:38 PM PDT by billorites (freepo ergo sum)
[ Post Reply | Private Reply | To 2 | View Replies]

To: ConservativeMind

Formerly known in the Midwest as Microdot.
....so I’ve been told.


4 posted on 09/05/2023 3:12:19 PM PDT by lee martell
[ Post Reply | Private Reply | To 1 | View Replies]

To: lee martell

Formerly known in the Midwest as Microdot.
....so I’ve been told.


Microdot was LSD or acid, not mushrooms.
Totally different drug.
....didn’t need to be told.


5 posted on 09/05/2023 3:20:08 PM PDT by AirForceVet1988 ("As the pattern gets more intricate and subtle, being swept along is no longer enough.")
[ Post Reply | Private Reply | To 4 | View Replies]

To: lee martell

Sir, I believe that was Lysergic acid diethylamide (LSD), at least it was back in my days. Regards.


6 posted on 09/05/2023 3:20:12 PM PDT by kawhill (kawhill)
[ Post Reply | Private Reply | To 4 | View Replies]

To: ConservativeMind

“One pill, with non-drug follow up, can remediate depression.”

That’s been known for a while. Hey, I trust Pfizer.


7 posted on 09/05/2023 3:27:12 PM PDT by dljordan
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind
Back in the day these came frozen or dried. Their hallucinogenic properties have been known for thousands of years. Mesoamerican natives, such as the Aztecs and Mazatecs used them.


Magic Mushrooms / Psilocybin mushrooms

8 posted on 09/05/2023 3:28:38 PM PDT by Bounced2X (Boomer - I survived childhood with no bike helmet.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: lee martell

“Formerly known in the Midwest as Microdot.”

Purple Owlsey was a favorite.


9 posted on 09/05/2023 3:28:52 PM PDT by dljordan
[ Post Reply | Private Reply | To 4 | View Replies]

Have dinner and breakfast with a beautiful woman


10 posted on 09/05/2023 3:36:43 PM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

does 50 years ago count? been really happy for 50 years so....


11 posted on 09/05/2023 3:38:59 PM PDT by Qwapisking ("IF the Second goes first the First goes second" L.Star )
[ Post Reply | Private Reply | To 1 | View Replies]

To: Qwapisking

Sir, had to look at your handle, specifically about good quotes. Here is one I think: William Congreve, 1697. “Music hath charms to soothe the savage breast. To soften rocks, or bend the knotted oak.” Regards, kawhill.


12 posted on 09/05/2023 3:45:27 PM PDT by kawhill (kawhill)
[ Post Reply | Private Reply | To 11 | View Replies]

To: ConservativeMind

Sure, eating a shroom was like really far out man. Still felt way cool six weeks later.


13 posted on 09/05/2023 3:52:51 PM PDT by hinckley buzzard ( Resist the narrative.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: billorites

Hunter S. Thompson would said that’s fine if you can handle seeing those formations of screeching bats flying overhead.


14 posted on 09/05/2023 3:53:04 PM PDT by frank ballenger (You have summoned up a thundercloud. You're gonna hear from me. Anthem by Leonard Cohen)
[ Post Reply | Private Reply | To 3 | View Replies]

To: dljordan
Purple Owlsey was a favorite.

"This is a type of acid (LSD) that was engineered by LSD chemist Owsley Stanley. The super pure acid that Owsley produced was a staple of the Bay Area scene in the mid to late 60′s, showing up at Grateful Dead shows."

Owlsey was pointed out to me backstage, in the catering area, at the first Dead show I ever worked. Our production manager told me not to eat the spaghetti. The sauce could be dosed, said happened to him once.


Owsley Stanley, left, with Jerry Garcia of the Grateful Dead

15 posted on 09/05/2023 3:53:47 PM PDT by Bounced2X (Boomer - I survived childhood with no bike helmet.)
[ Post Reply | Private Reply | To 9 | View Replies]

To: ConservativeMind

Thinking you can fly,

cuz shrooms,

and jumping of a tall building

cures all known forms of

depression permanently.

These people proposing this are evil.

.( I do remember the 60’s and mushroom heads and deaths )


16 posted on 09/05/2023 3:54:55 PM PDT by cuz1961 (USCGR Veteran )
[ Post Reply | Private Reply | To 1 | View Replies]

To: lee martell

As I recall reading, some very bright chemists discovered this compound known as ergot, a fungus growing on rye plants and how the hell they discovered the hallucinogenic properties of that I will never understand.


17 posted on 09/05/2023 4:07:37 PM PDT by kawhill (kawhill)
[ Post Reply | Private Reply | To 4 | View Replies]

To: ConservativeMind

Used to check Cow patties for them. Chewed on the elusive peyote. Never licked a toad or drank th hiauasca.


18 posted on 09/05/2023 4:16:46 PM PDT by waterhill (I Believe!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: kawhill
As I recall reading, some very bright chemists discovered this compound known as ergot, a fungus growing on rye plants and how the hell they discovered the hallucinogenic properties of that I will never understand.

Albert Hoffman.

He began studying the medicinal plant Drimia maritima (squill) and the fungus ergot as part of a program to purify and synthesize active constituents for use as pharmaceuticals. His main contribution was to elucidate the chemical structure of the common nucleus of the Scilla glycosides (an active principle of Mediterranean squill). While researching lysergic acid derivatives, Hofmann first synthesized LSD on 16 November 1938. The main intention of the synthesis was to obtain a respiratory and circulatory stimulant (analeptic) with no effects on the uterus in analogy to nikethamide (which is also a diethylamide) by introducing this functional group to lysergic acid. It was set aside for five years, until 16 April 1943, when Hofmann reexamined it and discovered its powerful effects. He described what he felt as being:

... affected by a remarkable restlessness, combined with a slight dizziness. At home I lay down and sank into a not unpleasant intoxicated[-]like condition, characterized by an extremely stimulated imagination. In a dreamlike state, with eyes closed (I found the daylight to be unpleasantly glaring), I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours this condition faded away.

Three days later, on 19 April 1943, Hofmann intentionally ingested 250 micrograms of LSD, which he thought would represent a prudently safe, small amount, but was in fact a strong dose. At first, his trip was not pleasant, as people appeared to morph into fantastic creatures, office furniture moved and shifted like living entities, and he felt possessed by otherworldly forces.

April 19 is now widely known as "Bicycle Day", because as Hofmann began to feel LSD's effects, he tried to ride to the safety of his home on his bike. This was the first intentional LSD trip in history.

Hofmann's research with LSD influenced several psychiatrists, including Ronald A. Sandison, who developed its use in psychotherapy. Sandison's treatment at Powick Hospital in England received international acclaim.

Hofmann continued to take small doses of LSD throughout his life, and always hoped to find a use for it. In his memoir, he emphasized it as a "sacred drug": "I see the true importance of LSD in the possibility of providing material aid to meditation aimed at the mystical experience of a deeper, comprehensive reality."

19 posted on 09/05/2023 4:29:51 PM PDT by Gunslingr3
[ Post Reply | Private Reply | To 17 | View Replies]

To: ConservativeMind
Big Pharma would disagree.
20 posted on 09/05/2023 4:32:30 PM PDT by CodeJockey
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-29 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson