No doubt a farm of CIA pilots in Nevada is flying these things.
Most of these aren’t “flown”. I expect they have a GPS guidance package with target coordinates entered prior to launch. If satellite recon passes often enough the target coordinates for aircraft on an airfield could easily be updated in time to catch it with a drone, if it sits still for 24 hours or so. Lag time would be many hours, given flight times to a range of 1000km.
They may also have some version of a Starlink receiver. The Naval drones do. Those would be “flown”, probably, though I don’t know how well that would work to perform fine control for an aircraft. The naval drone videos seem laggy.