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The article is interesting, but provides little opportunity to help until the end, where it’s said that mitochondria in MS nerve cells may increase myelin damage from oxygen or “free” radicals.

There appear to be three simple ways, described in prior studies I’ve posted, to help mitochondria quench free radicals throughout our bodies, as we age. One is on-the-spot, within the mitochondria, creation of glutathione a major body-made antioxidant. Studies have shown glycine and NAC (GlyNAC), in roughly equal amounts, helps to do just that. The second is via superoxide dismutase (SOD), also made in the cell, which can be greatly enhanced by adding taurine, at least 500 mg, three times a day. Finally, our cells all have an ion-channel reserved for routing one specific food antioxidant, ergothioneine, into mitochondria. Unfortunately, the main way our bodies get this is from mushrooms. Oyster and other non-button mushrooms have quite a bit more of this. If we aren’t eating mushrooms, we likely get little-to-none. It’s optional, though. Ergothioneine is now available in supplement form, as well, thankfully.

However, the devil is in the details, here. Glutathione and SOD only hold up a matter of hours against the mitochondrial free radicals before being used up. This is where ergothioneine is an amazing help. Due to the shape of ergothioneine and an innate ability for mitochondria to regenerate ergothioneine, the antioxidant lasts up to three to four weeks.

There is a fourth option called “MitoQ,” but it is a man-made molecule that lasts under a day, and may cause problems with kidney cells, according to a study. It’s also a more expensive supplement.

None of this would reverse MS, but, if the comment from the study about mitochondria holds true, these items could reduce a key form of ongoing damage.

The nice thing is that these are easy to supplement, which is important for older people, as we somehow stop producing enough conditional amino acids (glycine, cysteine, and taurine (from cysteine)) to properly protect our bodies.

1 posted on 05/28/2023 10:08:45 AM PDT by ConservativeMind
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2 posted on 05/28/2023 10:09:43 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

GlyNAC threads:

https://freerepublic.com/tag/glynac/index?tab=articles

Taurine threads:

https://freerepublic.com/tag/taurine/index?tab=articles

Ergothioneine threads:

https://freerepublic.com/tag/ergothioneine/index?tab=articles

MitoQ threads:

https://freerepublic.com/tag/mitoq/index?tab=articles


3 posted on 05/28/2023 10:20:41 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Low-dose(1.5mg-4.5mg) naltrexone may help this and other autoimmune diseases https://www.lowdosenaltrexone.org/ . It’s been known since 1985, but the FDA can’t seem to get around to testing it.


4 posted on 05/28/2023 10:35:08 AM PDT by devere
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