If we run DeSantis, maybe we have a chance. Biden will be pressured to debate DeSantis. DeSantis will make sure that he can have some say on who's the moderator in the debates. Biden will have to campaign against DeSantis.
I remember the VP Biden-Ryan debate in 2012. Everyone thought Ryan would eat Joe alive, especially on budget issues. Ryan was a data guy. Joe demolished him essentially by lying and making things up. Fact checking after the debate was futile. Most viewers don’t hear the corrections. The damage is done.
Joe is an inveterate liar. He lies about everything. Even when confronted with the truth, Biden will say that it isn’t true. Joe would make mincemeat out of DeSantis. It took the first debate for Trump to figure Biden out. He was beating the crap out Biden in the 2nd debate until the moderator intervened on behalf of Biden.