In most cases - from what I’ve read - for those enduring full conversion (M to F, or F to M) the side effects include urinary incontinence, failure in achieving orgasm, and new, putrid body odors. Then depression sets in.
Thats just the surface of what they endure. Many are in terrible physical pain and all kinds of gross side effects. They realize what a terrible, awful mistake theyve made Irreversible Damage as Abigail Shrier says in her book
...and the mental illness underlying it all is never fully addressed.
Therefore, a very high suicide rate among these unfortunate people.