[Varda]

“most drastic effects occurring in obese men”

Among the hardwired differences between male and female is that obesity produces different hormones. Obese females have too much testosterone and obese males have too much estrogen.
Add more on top of that and the problems multiply.

[Basket_of_Deplorables]

“Among the hardwired differences between male and female is that obesity produces different hormones. Obese females have too much testosterone and obese males have too much estrogen.
Add more on top of that and the problems multiply.”

Exactly! See my post right above this.