P53 repression is a well known issue, and it's involved in cancers of many different tissues of origin. P53 is the most frequently mutated gene in human cancers.
My son has recovered from an unusual cancer of the neck, my brother had an operation for colon cancer and now is receiving chemo for liver metatsteses, and my partner has been treated for prostate cancer with radiation and for another year, anti-testosterone shots. So I have been doing on-line research on cancer and natural treatments.
I had been taking Astaxantin, and other items. to improve my cataracts (successfully). I had also sent some to my brother for his cataracts. Then I read an article which said that astaxantin helps with cancer. It appears it can increase apoptosis (natural cell death) in cancerous tissue while at the same time reducing apoptosis in surrounding normal tissues. So now I am also giving it to my partner.
In 2020 I had learned from Dr. Zelenko that zinc is a virus killer, and that HCQ (an ionophore) helps zinc get into the Covid virus infected cells to destroy the virus. I also learned there were a number of other ionophores (something that changes the electrical charge on the zinc). Ivermectin appears to act as one, and Quercetin, which can be bought without a doctor’s prescription. EGCG and resviritrol seem to also be ionophores and there are more. I then read a science article regarding study of zinc content of nine common cancers. They found that all nine cancer tissues were deficient in zinc, even though surrounding normal tissues were normally or even well supplied with zinc. This article also suggested it might be good to see if an ionophore I had not heard of before might be studied to see if it could get zinc into the cancer virus infected cells. So now I am giving my partner and brother zinc and Quercetin as well as Astaxanthin.
I also read that Vitamin E may interfere with Astaxantin, so I have started taking my Vitamin E in the midday since I take the Astaxantin morning and evening. So much to discover and I am still looking.