CRISPR is capable of silencing genes and inserting genes. It may be possible, in time, to silence the male gene and add female.
Here’s an example with pigs: https://www.synthego.com/blog/crispr-pigs-xenotransplantation
Paganism is the belief that you can bend the universe to your own rules.
That’s what changing gender is part of, bending the universe to your own rules.