What kind of time period were the 4 jabs administered over? Asking on behalf of a vaxxed family member.
Mice immunization strategy
50 μg RBD recombinant protein (Sinobiological: #40592-V05H) was dissolved in 100 μL PBS and then formulated in Freund’s complete adjuvant (Sigma: #9007-81-2) or Freund’s incomplete adjuvant (Sigma: #F5506-10ML) at a ratio of 1.2:1. Four subcutaneous immunizations were administered in conventional group (at Weeks 0, 2, 4, and 6). Or six subcutaneous immunizations were administered in extended group (at Weeks 0, 2, 4, 6, 9, and 12). On day 10 after each immunization, tail vein blood was collected and immediately used for antibody analysis.