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If you are on metformin, it appears it is correcting something in diabetes that encourages the breakdown of one’s joints.

All sorts of dysfunction comes out of diabetes, unfortunately.

1 posted on 12/19/2022 8:25:02 PM PST by ConservativeMind
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2 posted on 12/19/2022 8:25:30 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

My next question would be whether people on Metformin have lower joint replacement rates than non-diabetics (who obviously would not be on Metformin).

If that’s the case, then Metformin is providing a protection not otherwise available to anyone, and leads to the possibility of taking the drug, perhaps in much lower doses for non-diabetics, to prevent degradation of joints.

Probably a long-shot, but since no one knows how drugs work, anything is possible.


3 posted on 12/19/2022 9:41:26 PM PST by BobL
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To: ConservativeMind

I’d say that T2 diabetics tend to be far heavier (on average) which causes the joint damage (especially the knees) vs the diabetes itself. Metformin usage tends to lower weight but I don’t think it would be weightloss alone that would be the benefit.

Otherwise this would be helpful towards T1 diabetics too.


4 posted on 12/19/2022 9:48:09 PM PST by Skywise
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To: ConservativeMind
That's good to know.   I have been on Metformin for fifteen years.   My brother has had both hips replaced and he has been on Metformin for years too, but he always weighted more then I did through the years.   About twenty months ago I threw out my hip when exercising in a crazy way.

I had been using a treadmill at the maximum degree of incline at about four miles per hour but my treadmill finally gave up the ghost.

I ordered a new Bowflex Max 10 trainer but it had a long backlog.   While I waited, I started running in a figure eight around my basement but my track had a sharp turn that I took too hard and there went my hip.   I re-injured my broken ankle from the 1980's at the same moment.

I could still walk so I tried to tough it out.

I ordered a year and a half of Puritan's Pride Hydrolyzed Collagen 1000 mg and took eight pills a day.   I knew it was the real thing because it tasted like a cow horn.   My wife looked at me funny and asked how I knew what a cow horn tastes like?

Well, when we were kids, somebody always had a horn made from a cow's horn and they were always passed around for a turn.   When the spittle and breath goes through a cow horn horn from blowing through it so much, you can't help but taste it.

Those Collagen pills were 5/8ths of an inch long, I took 8 a day and they tasted like the cow's horn horns of my youth.   It's not very pleasant.

I cannot say I am 100% better but I am three months from Seventy so how would I really know?   Still, it's good to know I have my Metformin on my side.

5 posted on 12/19/2022 11:19:31 PM PST by higgmeister (In the Shadow of The Big Chicken!)
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To: ConservativeMind

NB


6 posted on 12/20/2022 5:02:58 AM PST by Mercat
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To: ConservativeMind

Just got back from annual visit. 8.1 A1c. Gotta get that back down. Dr. upped my metformin from 500mg am/pm to 1000mg am/pm. suggested a twice a week shot to help A1C and lose weight. Gotta hit the gym at age 51 with 32BMI.


7 posted on 12/20/2022 5:42:39 AM PST by DCBryan1 (Delete FB, TWTR, GOOGL, AMZN, YHOO, Gmail/chrome. Use Gab, Brave + DDG, VPN, Freerepublic )
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To: ConservativeMind

bkmk


9 posted on 12/20/2022 6:52:17 AM PST by sauropod (Fascists also buy Comcast cable packages" - Olby - Wanna buy mine?)
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To: ConservativeMind

I havent seen anybody commit on the side affect that my wife and I both experienced while taking Metformin and that our doctors told us was common and that was dire rear.

Spell check says I’m not even close to spelling diaria correctly.


10 posted on 12/21/2022 1:14:39 AM PST by Graybeard58
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