Let me put it this way.
Most are sterile and can’t have children.
Once they start the hormones and/or have the surgery they will be patients for life.
The suicide rate for them is over the top.
Telling (by your actions) the Lord that He made a mistake when He made you probably never goes over well.
Fortunately, the Father can make proverbial camels get through the eyes of needles and just as He had Paul write there is a “such were some of you” in repentance.
But to those who remain a such are you still it only ends bad for them.