[mewzilla]

From April...

Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccines

...anaphylaxis and other manifestations of hypersensitivity can be considered as very rare adverse events. Although current recommendations include avoiding a second dose in those with first-dose anaphylaxis, the underlying mechanisms are unknown; therefore, the risk of a future reaction cannot be predicted...

Okaaaay...

[gas_dr]

There is no such thing as first dose anaphylaxis. Anaphylaxis only occurs on subsequent exposures to allergens. There can be analphylactoid reaction but is an entirely different mechanism.