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It would appear senescent cells help create conditions for depression. These are cells that remain in our bodies, but do not get recycled, as they did when we were younger. It is largely responsible for the effects of aging we notice.

There are now proven ways to address this, to a large extent. Senolytics are drugs and supplements that cause apoptosis of cells, which is the natural elimination of dysfunctional cells our bodies used to always use. Cell parts get recycled. Doing this in older people has been found to be helpful.

Other options revive the cells. GlyNAC does this by removing cellular inflammation. In studies, it allowed 80 year olds to have a walking gait that was faster than that of 30 year olds, for instance, along with many other health factors nearing that of 30 year olds. Also, a supplement called Urolithin A forces mitophagy, which is the apoptosis of just the defective mitochondria in our cells, followed by new mitochondria to replace those just eliminated. Mitochondria our the energy powerhouses in our cells. Imagine taking both together! (My wife and I are currently trying this.)

These have all been previously posted, here on Free Republic, if interested. The GlyNAC daily amount Nestle Celltrient suggests (it bought the patent) is 1,200 mg of glycine and 1,200 mg of NAC a day, but the study with the 80 year olds used over five times that amount. You can make GlyNAC cheaply from those two amino acids bought from a store. For the Urolithin A, which is also available from Nestle, 500 or 1,000 mg a day is what has been used in human trials.

Prior senolytic threads described apigenin, fisetin, and quercetin as possible senolytic options.

1 posted on 08/11/2022 9:35:58 PM PDT by ConservativeMind
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

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2 posted on 08/11/2022 9:36:38 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Is the biomarker the presence of XX chromosomes in the home?


3 posted on 08/11/2022 9:55:02 PM PDT by Deaf Smith (When a Texan takes his chances, chances will be taken that's for sure.)
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To: ConservativeMind

Amazing stuff. Bookmark.


4 posted on 08/11/2022 10:53:07 PM PDT by kelly4c
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To: ConservativeMind

bk


5 posted on 08/12/2022 5:07:20 AM PDT by xenia ( “Freedom is the right to tell people what they do not want to hear.” George Orwell)
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To: ConservativeMind

bookmark


6 posted on 08/12/2022 6:16:26 AM PDT by Cats1
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