Posted on 07/01/2022 6:02:31 AM PDT by onthelookout777
Thanks for reply.
Sometimes my quick skimming misses those details....or perhaps I need more B1 and B12. :-)
GaltAdonis, thanks for the Benfotiamine information.
My pleasure.
B1 helps when you can't shut off your brain, when it is racing from subject to subject. 100 mg.
There is a type of dementia called Wernicke–Korsakoff syndrome that is caused by thiamine deficiency. It is common in alcoholics.
Sulbutiamine is also used as a nootropic (smart pill), which suggests brain-thiamine deficiancy may be common.
:-)
YW!!
Regarding safety of taking high-dose thiamine/B1:
Harvard School of Public Health:
Thiamin - Vitamin B1
... UL: A Tolerable Upper Intake Level (UL) is the maximum daily dose unlikely to cause adverse side effects in the general population. There is no UL for thiamin due to a lack of reports showing negative effects from high thiamin intakes.
... Toxicity
It is unlikely to reach a toxic level of thiamin from food sources alone. In the setting of very high intakes, the body will absorb less of the nutrient and flush out any excess amount through the urine. There is no established toxic level of thiamin.
https://www.hsph.harvard.edu/nutritionsource/vitamin-b1/
_______________________________________________
NHS (National Health Service) in the UK:
... Mild thiamine deficiency – the usual dose for adults is between 25mg and 100mg, taken once a day.
Severe thiamine deficiency – the usual dose for adults is 100mg, taken 2 or 3 times a day...
What if I take too much?
Thiamine is generally a very safe medicine. Taking too much is unlikely to harm you or your child. If you’re worried, speak to a pharmacist or doctor.
Side effects
Like all medicines, thiamine can cause side effects in some people. But most people have no side effects or only minor ones.
Common side effects
Talk to a pharmacist or doctor if these side effects bother you or do not go away:
feeling sick (nausea)
diarrhoea
stomach ache
Serious allergic reaction
In rare cases, thiamine can cause a serious allergic reaction (anaphylaxis).
https://www.nhs.uk/medicines/thiamine-vitamin-b1/
ping
Looks like Thiamine deficiency is a very common occurence, and very scary. It seems to be easily undiagnosed by the medical cabal. The article by Marrs and Lonsdale is very interesting.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533683/
About 10% of thiamin is also lost due to freezing of foods.
Benfotiamine is fat soluble and stays longer in the body.
Great article. Thanks for posting!
I think the article that I posted is one that onthelookout was trying to post. He(?) deserves the credit.
Any advantages/disadvantages of a higher dose - i.e. 500mg?
A Harvard study says any excess amount just gets flushed out of the body. What I don’t know is if long term excess usage affects other vitamins in the body.
That’s also been my understanding of vitamins...”any excess amount just gets flushed out of the body”
I’m searching for a time release version of B1 to obtain a more even dose throughout the day,
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