VERY interesting.
My wife is a long term multiple myeloma survivor.
She was diagnosed very late, but survived because of TWO autologous stem cell transplants. Since then she’s had pretty much every new treatment for multiple myeloma. It relapses, she gets a new treatment, it is brought under control, rinse and repeat.
HOWEVER, her most recent labs show what we and her oncologist suspect is two separate myeloma clones (a second clone is rare, but happens with myeloma patients that have been treated heavily, and survived as long as she has). I had not heard of this particular variant, but her recent labs are consistent with what is described here.
Regardless, it appears treatment for the new variant described in this article would be the same as she is currently getting to bring her most recent relapse under control.
So, in a practical sense, this is worthwhile information but not something that will change what we are currently doing.
Thanks for posting!