[ConservativeMind]

I apologize, but I thought I had already posted this. I have a lot of studies I have saved from the past that I haven’t put up on Free Republic (there are too many good things to post and it’s hard to keep ahead of the new studies).

This is available as a supplement from Nestle (over a $1 a day), which bought the rights to the patent, but you can make this from 600 mg of glycine (capsule or powder) and 600 mg of N-Acetyl Cysteine (NAC), taken together, without other supplements, each day. The cost to make it yourself can be as low as 12 cents a day.

This is a really amazing elixir, made from two conditional amino acids we apparently can’t make enough of as we age. It also wasn’t known these amino acids did so much to make mitochondria work, or work again, if the cells had entered senescence.

Everyone should be considering this supplement.

[ConservativeMind]

The study:

Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial

https://onlinelibrary.wiley.com/doi/10.1002/ctm2.372

[ConservativeMind]

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[nickcarraway]

Is that supplement even available?

[sauropod]

.

[cdcdawg]

“Everyone should be considering this supplement.”

I’m waiting on whatever makes Biden sound like a competent person. Granted, he never was, so a supplement that turns back the clock will only get us a younger idiot in his case.

[jonrick46]

Ping

[susannah59]

Why should they be taken without other supplements? Absorption issues? And how long should the time interval be, regarding other supplements?

[old-ager]

Does anyone have any thoughts about just using glutathione?

[saintgermaine]

I have been taking this combination for a long time along with other supplements. Unfortunately, it doesn’t do anything for my bad left hip as well as my left knee. But I guess you just can’t win them all.

[StAntKnee]

I consider this a valuable post. Thank you.

[Ancesthntr]

“…you can make this from 600 mg of glycine (capsule or powder) and 600 mg of N-Acetyl Cysteine (NAC), ….”
—————
Can TMG be used instead of “plain” glycine? I already take a teaspoon in my coffee every morning, and 1200 mg of NAC every other day.

[Nifster]

Interesting. Thanks

[jonrick46]

This is sold at Amazon for $40 for 60 capsules:

[Secret Agent Man]

Look for this to never behind behind your pharmacists’ counter, ever.

[null and void]

bkmk

[clintonh8r]

mark

[Bob434]

i think there is a precaution for one or the other of them if a person has allergies to sulfur-

[jimwatx]

In lifespan studies in mice, the 24% improvement was the exact same for both GlyNAC and N-acetylcysteine itself. And as mentioned above it’s much cheaper just to buy the amino acids themselves rather than this overpriced hyped pill.

https://joshmitteldorf.scienceblog.com/

[bimboeruption]

Thanks for the info. I’m going to give this a try.

[TheEditor]

Setria has been around a long time and is proven effective. More expensive though. I used to buy it from the guy who patented the formulation, Dr Harry Demopoulos.