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For spraying for most spiders the safest and most effective is Bayer Tempo SC. We use it in our seed barn, on concrete floor. It will kill weevils and crickets for years after spraying inside the building. It kills most spiders. Not Black Widows.

If that does not work you can step up to Bayer Temprid. It even kills bedbugs. Residual lasts for 6 months.

Now, treating the bites? I've been bitten by Brown Recluse spiders 2 times. Simplest treatment is cut down a nitro patch the size of the bite area and leave it for a couple of days. It will dilate the blood vessels and allow the body to clean up the venom. Everyone who tried this has succeeded in clearing up the bite.

I have even used 1/4 of a nitro tablet on top of bite, one drop of water to dissolve, covered with band-aid for a couple of days. Always works.

There was a doctor in Ft. Worth that regularly treated his patients with this.