The moon has supplies of H3, which I’ve read would be useable as rocket fuel. This would make the moon the gas station for flights around the solar system.
I highly recommend "Moon". A great SF movie on this very topic.
I suppose He3 might be usable as rocket fuel, but it’s really desired as a possibly more viable path to nuclear fusion than tritium and deuterium. Still, we don’t actually have the technology to make viable fusion reactors even if we had access to all the He3 on the moon, so right now it’s not even usable for that.