A gram of fentanyl would work every time.
Midazolam + Fentanyl is exactly what they prescribe for many patients on ventilators. No wonder so may die.
https://pubmed.ncbi.nlm.nih.gov/16540957/
Objective: To compare the efficacy of continuous intravenous sedation with midazolam alone vs. midazolam plus fentanyl (”co-sedation”) during mechanical ventilation.
Conclusions: In mechanically ventilated patients, co-sedation with midazolam and fentanyl by constant infusion provides more reliable sedation and is easier to titrate than midazolam alone, without significant difference in the rate of adverse events.