Sure, but that’s no different than the “power of positive thinking”, “visualization” or any number of other “self help” games.
And that’s if we just discount all the harm it can do. For example, what if someone won’t date a person because “our signs aren’t compatible”? That may have been the perfect match for them, but they’ll never know because they let themselves get bamboozled.
If someone doesn't want to date me because of Zodiac signs, they probably aren't for me.