| In the General/Chat forum, on a thread titled Has the virus been isolated? Yes.So why aren't we doing experiments on animals to determine the safety and efficacy of the COVID vaccines? Answer: Because nobody wants to know the answer., Brian Griffin wrote: |
“Since 2005, all the animal trials were failures so you think there’s no value in animal trials? The animals got ADE....” Could you provide one or more links, please! |
Here, I'll get you started.
From Christian Elliot's April 2021 article, 18 Reasons I Won't Be Getting a Covid Vaccine (deconstructingconventional.com):
#3: THE UGLY HISTORY OF ATTEMPTS TO MAKE CORONAVIRUS VACCINES
There have been many attempts to make viral vaccines in the past that ended in utter failure, which is why we did not have a coronavirus vaccine in 2020.
In the 1960's, scientists attempted to make an RSV (Respiratory Syncytial Virus) vaccine for infants.
In that study, they skipped animal trials because they weren't necessary back then.
In the end, the vaccinated infants got much sicker than the unvaccinated infants when exposed to the virus in nature, with 80% of the vaccinated infants requiring hospitalization, and two of them died.
After 2000, scientists made many attempts to create coronavirus vaccines.
For the past 20 years, all ended in failure because the animals in the clinical trials got very sick and many died, just like the children in the 1960's.
You can read a summary of this history/science here.
Or if you want to read the individual studies you can check out these links:
In 2004 attempted vaccine produced hepatitis and liver damage in ferrets
In 2005 mice and civets became sick and more susceptible to coronaviruses after being vaccinated
In 2012 the ferrets became sick and died. And in this study mice and ferrets developed lung disease.
In 2016 this study also produce lung disease in mice.
The typical pattern in the studies mentioned above is that the children and the animals produced beautiful antibody responses after being vaccinated.
The manufacturers thought they hit the jackpot.
The problem came when the children and animals were exposed to the wild version of the virus.
When that happened, an unexplained phenomenon called Antibody Dependent Enhancement (ADE) also known as Vaccine Enhanced Disease (VED) occurred where the immune system produced a "cytokine storm" (i.e. overwhelmingly attacked the body), and the children/animals died.
Here's the lingering issue...
The vaccine makers have no data to suggest their rushed vaccines have overcome that problem.
In other words, never before has any attempt to make a coronavirus vaccine been successful, nor has the gene-therapy technology that is mRNA "vaccines" been safely brought to market, but hey, since they had billions of dollars in government funding, I'm sure they figured that out.
Except they don't know if they have...
“Unexpectedly, Abs that neutralized most human S glycoproteins enhanced entry mediated by the civet virus S glycoproteins. The mechanism of enhancement involved the interaction of Abs with conformational epitopes in the hACE-2-binding domain. Finally, improved immunogens and mAbs that minimize this complication have been defined. These data show that the entry of severe acute respiratory syndrome coronaviruses can be enhanced by Abs, and they underscore the need to address the evolving diversity of this newly emerged virus for vaccines and immune therapies.”
https://www.pnas.org/content/102/3/797
Hopefully, the scientists at Pfizer and Moderna are at least as well informed as freerepublic blogger ransomnote.