from this study:
MCA can prevent successful vaccines
It appears that since the monoclonals attach to spike proteins it inhibits your body from producing antibodies if you are given an mRNA vaccine.
Likely since the government has gone all out on vaccines they don't want any drug messing with it. The GlaxoSmithKline monoclonal sotrovimab supposedly targets a different structure on the virus so wouldn't interfere. (pure speculation on my part)
Most recently a lab test of omicron using regeneron and Eli Lilly MCAs show poor efficacy:
German in vitro (lab) study on effectiveness against cultured omicron
This shows a reduction in neutralizing capacity of sera from vaccinated individuals and MCAs
It's funny the MCAs from Regeneron and Eli Lilly have success with other variants. There are no studies that I know of that indicate they are less effective when used on people with Omicron. Perhaps there is preliminary data from South Africa since Regeneron is not fighting this at all.
It seems very inconsistent. Ivermectin worked in a lab trial (although at a very high dosing). Yet no large trial in the US was ever done to even try to see if various dosing schedules would work.
Then 1 negative lab trial kills Regeneron and Eli Lilly MCAs even though they have been the best therapeutic to date without even a published trial in humans to see if it is indeed ineffective against Omicron.
I will let others draw conclusions from all of this.
There are only 55,000 doses in the US of sotrovimab since it is effective against other strains why wasn't the government stockpiling this medication as a back up to Regeneron and Eli Lilly MCA in case of shortages???
One final question. If the MCAs attach to the spike protein produced by the vaccines. How can the vaccines be effective against Omicron and the MCAs not be???
The German study seems to indicate that this is the indeed the case. But no let up on the mandates. Now I can answer this to some extent. Sera from a vaccinated human probably does not contain enough purified antibody at the levels of the MCAs in the test. So there may be some wiggle room in that.
I don’t think that’s quite accurate. Close though.
MAbs will kill off the virus before your own immune system can learn to make its own antibodies against the virus. So you won’t gain natural immunity from that infection.
To train your immune system you will either need to let the infection run untreated, with the risks that go with that, or get vaccinated.