I have tried to find my saved info about home treatments for Covid. I found everything except the antihistamine that is supposed to be effective against the virus. Can anyone help me out with a shortcut answer? Should have written it down.
famotidine (Pepcid) ?
Inflamm Res 2021 Jan;70(1):67-75.
doi: 10.1007/s00011-020-01422-1. Epub 2020 Nov 18.
Histamine receptors and COVID-19
Madeleine Ennis 1 , Katerina Tiligada 2
Abstract
Objective: Reports that the over-the-counter histamine H2 receptor antagonist famotidine could help treat the novel coronavirus disease (COVID-19) appeared from April 2020. We, therefore, examined reports on interactions between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and histamine receptor antagonists.
Methods: A systematic literature search was performed by 19 September 2020, and updated on 28 October 2020, in PubMed, Scopus, Cochrane Library and Google Scholar using (COVID-19 OR coronavirus OR SARS-CoV-2) AND (histamine antagonist OR famotidine OR cimetidine). ClinicalTrials.gov was searched for COVID-19 and (famotidine or histamine).
Results: Famotidine may be a useful addition in COVID-19 treatment, but the results from prospective randomized trials are as yet awaited. Bioinformatics/drug repurposing studies indicated that, among several medicines, H1 and H2 receptor antagonists may interact with key viral enzymes. However, in vitro studies have to date failed to show a direct inhibition of famotidine on SARS-CoV-2 replication.
Conclusions: Clinical research into the potential benefits of H2 receptor antagonists in managing COVID-19 inflammation began from a simple observation and now is being tested in multi-centre clinical trials. The positive effects of famotidine may be due to H2 receptor-mediated immunomodulatory actions on mast cell histamine-cytokine cross-talk, rather than a direct action on SARS-CoV-2.
Keywords: COVID-19; Histamine; Histamine receptor; Immunomodulation; Mast cells; SARS-CoV-2.
full text
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673069/
I printed out the protocol from Karl Denninger’s newsletter dated 9-24-2021 where he wrote about the nursing home in Spain that figured out how to treat its residents. Is that what you are remembering?
Anyway, the antihistamines recommended were cetirizine 10mg aka Zyrtec or loratadine 10 mg aka Claritin. The antihistamines were given every 12 hours.
There is a full protocol, and I can look to see if I saved the article if you would like.