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Vascular defects appear to underlie the progression of Parkinson's disease (Nilotinib stopped progression)
Medical XPress / Neurology Genetics ^ | Nov. 12, 2021 | Charbel Moussa, MBBS, Ph.D. et al

Posted on 11/22/2021 7:38:11 PM PST by ConservativeMind

click here to read article

Folks, this is an incredibly expensive drug, but, since they have found the issue to primarily be a vascular disease, cobbling together options to address that could be beneficial.
1 posted on 11/22/2021 7:38:11 PM PST by ConservativeMind
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To: ConservativeMind

I have a personal interest in this. I was diagnosed with Parkinson’s 5 years ago.


2 posted on 11/22/2021 8:43:50 PM PST by Blood of Tyrants (When elections fail, we will either live under tyranny or rebel and throw it off.)
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To: Blood of Tyrants

I’m sorry to hear this—my dad is now in his 15th year of Parkinson’s. My advice: when you take your LevaDopa, watch very carefully how it seems to work based on your sleep cycles and when you eat. My dad found eating less was best—he keeps a log tracking his symptoms with the meds because the doctors don’t really individualize the medication. They just prescribe it but there’s a real art to it—trial and error on the part of the patient.

I visited him today—his best hours are now between 10 am and noon. He says he “turns into a pumpkin” after 4 pm these days. So we are mindful of the rhythms of his day.


3 posted on 11/22/2021 9:53:51 PM PST by olivia3boys
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To: Blood of Tyrants

I was DX’ed 8 weeks ago. I read everything I can find on Parkinson’s. This sounds like the best yet.


4 posted on 11/22/2021 10:46:18 PM PST by muggs
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To: muggs

Fifteen years ago, a neurologist told me I had four of the five primary symptoms of Parkinsons.

Still trucking except for walking more slowly, sleeping poorly, and turning into a sleepy pumpkin about noon. Nap for an hour, repeat...


5 posted on 11/23/2021 1:33:31 AM PST by Does so (DC: "The Chinese city on top of a hill".)
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To: olivia3boys

I’ve hot my Sinemet dosages down pretty good. The trick is to find the balance between just enough to control the tremors and not enough to cause the dyskinesia.


6 posted on 11/23/2021 7:29:19 AM PST by Blood of Tyrants (When elections fail, we will either live under tyranny or rebel and throw it off.)
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To: muggs

Sorry to hear that. If you need any advice, send me a PM. I’ll be glad to discuss what I found that works.


7 posted on 11/23/2021 7:30:42 AM PST by Blood of Tyrants (When elections fail, we will either live under tyranny or rebel and throw it off.)
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To: muggs

And the best thing is to keep a positive attitude and do things that keep your hands busy (besides typing on the keyboard.) Parkinson’s is something you die with and not of. Check your Freepmail, I’m sending you my name and phone number so we can converse in private.


8 posted on 11/23/2021 7:33:34 AM PST by Blood of Tyrants (When elections fail, we will either live under tyranny or rebel and throw it off.)
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To: Blood of Tyrants

Thank you so much.

I have really stepped up my exercise. Just trying to stay busy. I am buying a pay of walking poles.

I will send you my number and real name too. I probably won’t have time to talk until Monday. Thanksgiving is keeping me busy.

I only know one person with Parkinson’s. We talk a little but he is pretty private.


9 posted on 11/24/2021 5:11:15 PM PST by muggs
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To: ConservativeMind

Bump for later reference


10 posted on 01/20/2022 10:22:30 AM PST by Senator_Blutarski
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