How many people have gotten monoclonal antibodies?
What adverse effects have been reported?
Many marketed drugs are based on monoclonal antibodies (mAbs) for different maladies. I posted a synopsis of how they are made, within the last year on this thread. (Sorry could not find it.)
They inherently are not bad, just a clone of one single antibody, grown in a cell culture system, collected and isolated. In response to infection, a mammal would typically generate polyclonal response, many different Abs to different proteins of the insult. If a specific protein is integral to a disease process, one approach would be to make Ab to it in an animal, then select out the best one, and amplify it as a mAb therapy. The mAb therapy would take out the protein to the disease process when administered.
Arthritis, cancer, virus...https://www.verywellhealth.com/what-is-a-monoclonal-antibody-189490