"...experts using such drugs for investigational purposes certify to such manufacturer or sponsor that they will inform any human beings to whom such drugs, or any controls used in connection therewith, are being administered, or their representatives, that such drugs are being used for investigational purposes and will obtain the consent of such human beings or their representatives , except where it is not feasible, it is contrary to the best interests of such human beings,..."
=> Explains a lot in retrospect.