Serena is done - she will never win another major tournament. The youngsters are not intimidated by her and they are in much better shape, younger and stronger. I never liked her as she often acted like a petulant child, both in winning and losing. I always thought - what do I know? I'm not a coach... - the secret to beating her was to make her run. She will tire out. Easier said than done when she is simply overpowering you though.
Venus seemed far kinder and classier, though not as good as Serena.