Incredibly dumb interpretation of Revelation?
How would it differ from this monstrosity?
To take the mark of the beast is to ascribe to a faction that is a known evil. Whether you believe that the COVID threat is real or not, taking a vaccine against an illness does not meet this requirement.
And requiring vaccinations has long been required for travel, school, and employment. In a couple of weeks, the EUA for the Covid vaccine will be moved to full approval. In that case, there will be no technical difference.