Jim Clark won the '65 Indy. Bobby Unser finished 19th. Jackie Stewart led most of the '66 race, and Clark finished 2nd. Graham Hill won it. So the mid-60s weren't exactly the American era at Indy.
That was back when most race cars that ran at Indy were front-engined using the four-cylinder Offenhauser engine. The success of the rear-engined race cars from England forced Indy racer designers to go to rear-engined cars by the late 1960's.