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To: 2aProtectsTheRest

He’s not the first person to postulate about the risks of viral escape caused by trying to vaccinate in the middle of a pandemic while mutations are still on the rise.

I am in no position to judge the situation but what he seems to be saying is there is a risk that the virus will mutate enough that it will evade the vaccine induced antibodies while at the same time the vaccine induced antibodies will limit the creation of innate antibodies by some mechanism e.g. crowded out by the artificial spike protein antibodies, or that the body tricks itself into thinking it is already working against the mutation when it isn’t.

Towards the end he discusses a little bit about his worry that with new variants still popping up, people may think they are immune but will end up becoming carriers for these mutations or catch this more severe strain and have limited natural ability to fight it. Again I’m in no position to judge just trying to absorb his postulate.


76 posted on 04/28/2021 4:30:32 PM PDT by monkeyshine (live and let live is dead)
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To: monkeyshine
"He’s not the first person to postulate about the risks of viral escape caused by trying to vaccinate in the middle of a pandemic while mutations are still on the rise."

It's sheer absurdity to claim that vaccinating while a disease is active in the population is a bad idea. If that were true, why did it work just fine with smallpox, polio, measles, mumps, rubella, varicella, diphtheria, etc.?

Why is it suddenly only now - after decades of successfully deploying vaccines to combat disease - that the vaccines are suddenly going to cause all these problems? Asking people to buy this nonsense is asking them to ignore observable reality and the history they've lived through.

We've seen what happens when you vaccinate while a disease is active: the disease goes away.

"There is a risk that the virus will mutate enough that it will evade the vaccine induced antibodies while at the same time the vaccine induced antibodies will limit the creation of innate antibodies by some mechanism e.g. crowded out by the artificial spike protein antibodies, or that the body tricks itself into thinking it is already working against the mutation when it isn’t."

That isn't how the human immune system works. At all. That's like saying there's a risk we're start floating into the stratosphere. No, there isn't, because that's not how it works.

Yes, viruses can mutate such that existing antibodies are reduced in effectiveness or so they stop working entirely. That happens all the time. It's why you need a flu shot every year and why the flu shot (which takes about 8 months to design and produce) is only 40-60% effective. Antigenic drift is something we've dealt with for decades. We're dealing with it now with SARS-CoV-2 and the South Africa, Brazil, and Indian variants. The existing vaccines are still very effective against all known variants, but a "booster" shot that's tuned for the new variants will be available in the fall to up the effectiveness against them.

There's no such thing as "innate antibodies". Antibodies are produced by B cell lymphocytes at the prompting of T cells specifically generated in the lymph nodes based on the antigens collected by dendritic cells and transported there. A very well done explanation of this process is available here. There is also no such thing as anything being "crowded out by the artificial spike protein antibodies". For one thing, there's no "artificial spike protein antibodies". That's not a real thing here. The COVID-19 vaccines available in the US work by getting cells to produce S proteins from SARS-CoV-2. Your body's dendritic cells grab those S proteins and take them to the lymph nodes, same as they would during an actual infection. From there, the process continues just as it would in infection, except there's no virus actually running around damaging tissues. And the body doesn't "trick itself". It produces antibodies against recognized antigens. If the antigen changes such that the antibodies won't work, it's a new antigen.

"Towards the end he discusses a little bit about his worry that with new variants still popping up, people may think they are immune but will end up becoming carriers for these mutations or catch this more severe strain and have limited natural ability to fight it."

Pure, unadulterated, fearmongering speculation without a shred of evidence to justify it. This has literally never happened in the history of human disease. It didn't happen with smallpox, nor polio, nor with the flu, nor measles, nor anything else. Will new variants emerge? Undoubtedly. Is it possible new ones will emerge which no existing antibodies work again? Sure. But if that's the case, nobody who recovered from a previous infection will fare any better than anyone vaccinated and we'll have a new vaccine prepared in short order to nip it in the bud.

This guy should back to working on dogs and cats. He's clearly putting out fearmongering nonsense on social media rather than publishing it in a scientific journal specifically to catch an audience unprepared to laugh at it as uneducated fearmongering. He's effectively treating you as a moron by posting this nonsense. I encourage you to do research for yourself into how the human immune system actually works (starting with the link I provided) so you too can laugh at this nonsense.

78 posted on 04/28/2021 7:58:21 PM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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