“What causes thrombotic thrombocytopenic purpura?
“A lack of activity in the ADAMTS13 enzyme (a type of protein in the blood) causes TTP. The ADAMTS13 gene controls the enzyme, which is involved in blood clotting. The enzyme breaks up a large protein called von Willebrand factor that clumps together with platelets to form blood clots.
Thrombotic Thrombocytopenic Purpura is a rare blood disorder that is considered a true medical emergency. TTP is diagnosed at a rate of 3-4in 1 million people per year. Potentially fatal complications can result from internal blood clotting, with damage to critical organs such as the brain and heart.