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BRUTUS in Antifederalist Paper 17 destroyed Madison's argument. Eventually Madison agreed and switched over to the Democrat-Republican Party once the after the Constitution was ratified because he started to witness first hand of how the weaknesses in the Constitution were being exploited by the Federalist.

"How far the clause in the eighth section of the first article may operate to do away with all idea of confederated States, and to effect an entire consolidation of the whole into one general government, it is impossible to say. The powers given by this article are very general and comprehensive, and it may receive a construction to justify the passing almost any law. A power to make all laws, which shall be necessary and proper, for carrying into execution all powers vested by the Constitution in the government of the United States, or any department or officer thereof, is a power very comprehensive and definite, and may, for aught I know, be exercised in such manner as entirely to abolish the State legislatures. Suppose the legislature of a State should pass a law to raise money to support their government and pay the State debt; may the Congress repeal this law, because it may prevent the collection of a tax which they may think proper and necessary to lay, to provide for the general welfare of the United States? For all laws made, in pursuance of this Constitution, are the supreme law of the land, and the judges in every State shall be bound thereby, anything in the Constitution or laws of the different States to the contrary notwithstanding. By such a law, the government of a particular State might be overturned at one stroke, and thereby be deprived of every means of its support."

The Necessary and Proper Clause led to the creation of the "Deep State".

I'm just curious, but if the anti-federalists were really correct that the Constitution would enable all that's been said that the anti-federalists foresaw, then why have the progressives moved heaven and earth to get around this obstacle known as the United States Constitution?

There's a disconnect somewhere. It might be me.