People are deluding themselves into thinking they are going to eliminate the Pythons there.
We got rid of Neanderthals and dodos.
Florida is a subtropical 'island' that was cleansed was f its tropical flora and fauna by the last glacial maximum and so it has many open ecological niches for introduced tropical species to thrive in.
When the current ice age kicks back into gear in about 15,000 years Florida will finally be free of the burmese python.