Sasse just got 67% of the vote in his race. Romney would have gotten a similar number, too. Little Marco is planning on using Hispanics as his base and MAGA voters are not his prioirty. These guys just do not care about what the GOP base wants. Never have. Never will.
If having big numbers in your own home state - whether Nebraska Utah or Florida - lets you buck the base while seeking the presidential nomination, then Jeb should have been our 2016 nominee.