I can see a need to alleviate some driving over the plains, where a driver can relax when he sees nothing before him fir miles and miles. Where he can, while keeping an eye on the road, also attend to his needs to make a small meal or just stretch out and take short naps.
I don’t believe AI can replace the driver. I do not believe AI has the ability to deal with unexpected things, like an incoming driver who has crossed lanes or ice and snow.
Knight Rider type AI is decades away probably, if ever.
KITT was compromised more than a few times. A rogue AI semi would be ugly.
Or hijackers. I can see defeating a truck’s electronics and activating the air brake system. Truck comes to a halt.