MedCram Lecture
May 11, 2020
Dr. Roger Seheult
Coronavirus Pandemic Update 69: “NAC” Supplementation and COVID-19 (N-Acetylcysteine)
N-Acetylcysteine (NAC) is an over the counter supplement that has been utilized by clinicians for years to treat acetaminophen (Tylenol) overdose, as a mucolytic, and for other medical problems. There is compelling research that NAC may also reduce the severity of viral infections like influenza, and perhaps reduce the risk of blood clots (thromboembolism) as well. Could NAC be effective in COVID-19? Dr. Seheult illustrates these ideas and discusses the peer-reviewed data involved.
https://www.youtube.com/watch?v=Dr_6w-WPr0w
linked paper:
...pre-clinical rationale for investigating NAC as a therapeutic to reduce thrombotic risk in MPN.
CHILDREN
* One in four children with severe COVID-19 develops organ failure, study finds (Texas Children’s Hospital, Houston)
* There also is the question of what role, if any, children play in spreading the new coronavirus. A study published last week by researchers in Germany found that infected children carry the same amount of the virus as adults, which indicates they might be as infectious.
40 of the Houston children had underlying conditions
German study:
” Analysis of variance of viral loads in patients of different age categories found no significant difference between any pair of age categories including children. In particular, these data indicate that viral loads in the very young do not differ significantly from those of adults. Based on these results, we have to caution against an unlimited re-opening of schools and kindergartens in the present situation. Children may be as infectious as adults.”