Citric acid? Sure... why not a little orange juice in your Covid-19-fighting tonic-and-gin?
Hydrogen peroxide
That may help as regards what is best. I took a little liberty in the public interest of adding some color and making boundary lines visible in the table from https://www.journalofhospitalinfection.com/article/S0195-6701(20)30046-3/fulltext
Biocidal agent |
Concentration |
Virus |
Strain / isolate |
Exposure time |
Reduction of viral infectivity (log10) |
Reference |
---|---|---|---|---|---|---|
Ethanol |
95% |
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 5.5 |
|
85% |
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 5.5 |
||
80% |
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 4.3 |
||
80% |
MERS-CoV |
Strain EMC |
30 s |
> 4.0 |
||
78% |
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 5.0 |
||
70% |
MHV |
Strains MHV-2 and MHV-N |
10 min |
> 3.9 |
||
70% |
CCV |
Strain I-71 |
10 min |
> 3.3 |
||
2-Propanol |
100% |
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 3.3 |
|
75% |
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 4.0 |
||
75% |
MERS-CoV |
Strain EMC |
30 s |
≥ 4.0 |
||
70% |
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 3.3 |
||
50% |
MHV |
Strains MHV-2 and MHV-N |
10 min |
> 3.7 |
||
50% |
CCV |
Strain I-71 |
10 min |
> 3.7 |
||
2-Propanol and 1-propanol |
45% and 30% |
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 4.3 |
|
SARS-CoV |
Isolate FFM-1 |
30 s |
≥ 2.8 |
|||
Benzalkonium chloride |
0.2% |
HCoV |
ATCC VR-759 (strain OC43) |
10 min |
0.0 |
|
0.05% |
MHV |
Strains MHV-2 and MHV-N |
10 min |
> 3.7 |
||
0.05% |
CCV |
Strain I-71 |
10 min |
> 3.7 |
||
0.00175% |
CCV |
Strain S378 |
3 d |
3.0 |
||
Didecyldimethyl ammonium chloride |
0.0025% |
CCV |
Strain S378 |
3 d |
> 4.0 |
|
Chlorhexidine digluconate |
0.02% |
MHV |
Strains MHV-2 and MHV-N |
10 min |
0.70.8 |
|
0.02% |
CCV |
Strain I-71 |
10 min |
0.3 |
||
Sodium hypochlorite |
0.21% |
MHV |
Strain MHV-1 |
30 s |
≥ 4.0 |
|
0.01% |
MHV |
Strains MHV-2 and MHV-N |
10 min |
2.32.8 |
||
0.01% |
CCV |
Strain I-71 |
10 min |
1.1 |
||
0.001% |
MHV |
Strains MHV-2 and MHV-N |
10 min |
0.30.6 |
||
0.001% |
CCV |
Strain I-71 |
10 min |
0.9 |
||
Hydrogen peroxide |
0.5% |
HCoV |
Strain 229E |
1 min |
> 4.0 |
|
Formaldehyde |
1% |
SARS-CoV |
Isolate FFM-1 |
2 min |
> 3.0 |
|
0.7% |
SARS-CoV |
Isolate FFM-1 |
2 min |
> 3.0 |
||
0.7% |
MHV |
10 min |
> 3.5 |
|||
0.7% |
CCV |
Strain I-71 |
10 min |
> 3.7 |
||
0.009% |
CCV |
24 h |
> 4.0 |
|||
Glutardialdehyde |
2.5% |
SARS-CoV |
Hanoi strain |
5 min |
> 4.0 |
|
0.5% |
SARS-CoV |
Isolate FFM-1 |
2 min |
> 4.0 |
||
Povidone iodine |
7.5% |
MERS-CoV |
Isolate HCoV-EMC/2012 |
15 s |
4.6 |
|
4% |
MERS-CoV |
Isolate HCoV-EMC/2012 |
15 s |
5.0 |
||
1% |
SARS-CoV |
Hanoi strain |
1 min |
> 4.0 |
||
1% |
MERS-CoV |
Isolate HCoV-EMC/2012 |
15 s |
4.3 |
||
0.47% |
SARS-CoV |
Hanoi strain |
1 min |
3.8 |
||
0.25% |
SARS-CoV |
Hanoi strain |
1 min |
> 4.0 |
||
0.23% |
SARS-CoV |
Hanoi strain |
1 min |
> 4.0 |
||
0.23% |
SARS-CoV |
Isolate FFM-1 |
15 s |
≥ 4.4 |
||
0.23% |
MERS-CoV |
Isolate HCoV-EMC/2012 |
15 s |
≥ 4.4 |
SARS = Severe Acute Respiratory Syndrome; MERS = Middle East Respiratory Syndrome; MHV = mouse hepatitis virus; CCV = canine coronavirus; HCoV = human coronavirus.
Copyright © 2020 Elsevier Inc. All rights reserved.