High prevalence of obesity in severe acute respiratory syndrome coronavirus (SARS-CoV-2) requiring invasive mechanical ventilation
Arthur Simonnet , Mikael Chetboun, Julien Poissy, Violeta Raverdy, Jerome Noulette, Alain Duhamel, Julien Labreuche, Daniel Mathieu, Francois Pattou
First published:09 April 2020
https://doi.org/10.1002/oby.22831
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1002/oby.22831
Abstract
Objective
The Covid-19 pandemic is rapidly spreading worldwide, notably in Europe and North America, where obesity is highly prevalent. The relation between obesity and severe acute respiratory syndrome coronavirus (SARS-CoV-2) has not been fully documented.
Methods
In this retrospective cohort study we analyzed the relationship between clinical characteristics, including body mass index (BMI), and the requirement for invasive mechanical ventilation (IMV) in 124 consecutive patients admitted in intensive care for SARS-CoV-2, in a single French center.
Results
Obesity (BMI > 30 kg/m2) and severe obesity (BMI > 35 kg/m2) were present in 47.6% and 28.2% of cases, respectively. Overall, 85 patients (68.6%) required IMV. The proportion of patients who required IMV increased with BMI categories (p < 0.01, Chi square test for trend), and it was greatest in patients with BMI > 35 kg/m2 (85.7%). In multivariate logistic regression, the need for IMV was significantly associated with male sex (p < 0.05) and BMI (p < 0.05), independent of age, diabetes, and hypertension. The odds ratio for IMV in patients with BMI > 35 kg/m2 vs patients with BMI < 25 kg/m2 was 7.36 (1.63-33.14; p=0.02)
Conclusion
The present study showed a high frequency of obesity among patients admitted in intensive care for SARS-CoV-2. Disease severity increased with BMI. Obesity is a risk factor for SARS-CoV-2 severity requiring increased attention to preventive measures in susceptible individuals.
Well, living in the most obese state in the country...i guess we’ll be shut down until morale improves or we lose weight.
Deaths at Virginia care facility with outbreak climb to 39
https://apnews.com/b9da44db9d5a1d1c06fc1aa48974c165
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150 cases of coronavirus found in 20 Lake County nursing homes
Each of the 20 long-term care facilities has at least two cases of COVID-19, Lake County health officials said, though they did not name the facilities. Officials could not be reached for further details Thursday morning.
The number of Lake County nursing homes with positive cases of COVID-19 has nearly doubled since last week
https://chicago.suntimes.com/2020/4/9/21214663/coronavirus-lake-county-20-nursing-homes-covid-19
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More Than 13 Percent Of Texas Nursing Homes Have At Least One Resident With Coronavirus, Officials Say
The disclosure comes after The Texas Tribune reported Wednesday that Texas was not sharing comprehensive data on nursing homes.
More than 160 of the state’s 1,222 nursing homes, or about 13%, have at least one case of the new coronavirus, state officials said Thursday. And 38 nursing home residents and staff members have died of COVID-19 statewide.