RE: where they are studying multiple agents and so far they are not that impressed with hydroxychloroquine in the severely ill. Maybe it’s use will be in the less I’ll.
If you look at the studies by Dr. Diduer Raoult in Marseilles on over 100 patients and the nearly 800 cases treated by Dr. Vladimir Zelenko in upstate New York, you will understand what Hydroxychloroquine is most effective at.
It is best used in conjunction with Azithromycin and Zinc and at the earlier stages of CoVid-19 illness as soon as symptoms like fever, cough, etc. are manifested.
When you administer these drug combo, it SHORTENS the patient’s time of stay in the hospital by several days and relieves the burden of hospitals. In other words you must administer them as soon as you can, not wait till the patient is so severely ill that he needs to be intubated. It does wonders for patients at the earlier stages of the disease nearly 99% of the time, preventing further disease progression.
What HCQ has NOT been show to be impressive, are for those whose lungs have been destroyed by the virus to a point where they need to be on ventilator.
There are cases where such patients have been saved and many have been posted here in FR, but the efficacy on patients at this later stage is not well established.
It remains to be seen if Remdesivir will do any better for later stage Covid-19 patients.
It’s efficacy anywhere is not well established. We are using it because so far it’s what we have but it is not likely to be the ultimate answer