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To: SeekAndFind

I know we don’t want to use up meds unnecessarily, but what about giving chlorquinone to high risk sick people at home in hope of preventing critical illness and need for more resources?

Cheap, old time proven drug, good safety margin, seems to be effective...

How much could we make, how fast?


18 posted on 03/16/2020 10:14:54 AM PDT by heartwood (Someone has to play devil's advocate.)
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To: heartwood

SOURCE: https://www.sciencenews.org/article/coronavirus-covid19-repurposed-treatments-drugs

TITLE: Repurposed drugs may help scientists fight the new coronavirus

EXCERPT:

Both remdesivir and the antimalaria drug chloroquine inhibited the new virus’s ability to infect and grow in monkey cells, virologist Manli Wang of the Wuhan Institute of Virology of the Chinese Academy of Sciences and colleagues reported February 4 in Cell Research. Remdesivir also stopped the virus from growing in human cells. Chloroquine can block infections by interfering with the ability of some viruses — including coronaviruses — to enter cells. Wang and colleagues found that the drug could also limit growth of the new coronavirus if given after entry. Chloroquine also may help the immune system fight the virus without the kind of over­reaction that can lead to organ failure, the researchers propose.


20 posted on 03/16/2020 10:23:33 AM PDT by SeekAndFind (look at Michigan, it will)
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To: heartwood

From the source I cited:

Chloroquine:

* Designed to treat: Malaria
* Evidence for: Lab tests against COVID-19
* Evidence against: No data

Remdesivir

* Designed to treat: RNA viruses (MERS, Ebola)

* Evidence for: Lab tests against the COVID-19 virus; animal tests against MERS; tests in people with Ebola

* Evidence against: Not as helpful as other drugs against Ebola


21 posted on 03/16/2020 10:25:25 AM PDT by SeekAndFind (look at Michigan, it will)
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