I use that stuff too occasionally, for convenience sake (or a generic)... But if you really need the compound for your headache, (assuming you take two of the Excedrine) take* 500Mg of Acetaminophen, 500 Mg of aspirin and drink some coffee, tea or cola for the caffeine.
*I’m not a doctor, nor a pharmacist, nor do I play one on the internet.
Head the warning labels.
There is Anacin (aspirin and caffeine)